Showing posts with label corona virus vaccine. Show all posts
Showing posts with label corona virus vaccine. Show all posts

Tuesday, January 19, 2021

மீ டூ காலம்! என்னடி எப்படி இருக்க? (48)

 நிலையாமை!

 இப்போ என்ன அவசரம்?  மாஸ்டர் ரிலீஸ் பண்ண?

 கொரோனா வைரஸ் ஆட்டிப் படைக்கும் இந்த நேரத்தில்!!

கொரோனா வாக்சின் எல்லாம் எல்லாரும் எடுத்த பிறகு ரிலீஸ் பண்ணலாமே?

இருந்தும் என்ன அவசரம்?

 இல்லண்ணா.. இந்த கந்து வட்டிக்காரன்..

 பிரச்சினை என்னனா செலவழிச்ச காசுக்கு வட்டி எவ்ளோ? கந்து வட்டிக்கு வாங்கிதான் படம் எடுக்கிறாங்க. போட்ட காசையாவது எடுப்போம் இலாபம் எல்லாம் வேணாம். இல்லைனா வட்டி நம்மள சாப்பிட்டு விடும் என்பதுதான் காரணம்.

நிச்சயம் பிகில் விலையில் பாதி விலைக்குத்தான் இந்தப்படம் விற்கப்பட்டு இருக்கும். ஓவர் சீஸ் மார்க்கட் ல 50% கலக்சன்தான்

ஆந்திரா கேரளா கர்நாடகால எல்லாம் பாதி விலைக்குத்தான் விக்க முடியும்? அதனால் படம் அல்ரெடி விநியோகஸ்தர்களுக்கு போட்ட தொகையை தந்துவிட்டதாம்

எவன் நெனச்சான். கொரோனா வைரஸ் பாதிப்பு ஏற்படும்னு

வாழ்க்கையே நிலை இல்லாத ஒண்ணுதான்.

சமூகப் பொறுப்பு இவனுக  தாலினு  சொல்லிக்கிட்டு திரிஞ்சவனுக்கெல்லாம் பணம்தான்டா இந்த நாய்களுக்கு அவசியம், மத்ததெல்லாம் ரெண்டாவதுதான் னு போட்டு ஒடச்சிருச்சு நம்ம கொரோனா வைரஸ்!!

***********************

"Hi!"

"Tell me"

"It came out negative, Caro darling"

"I knew that. You were just fucking with me"

"Nope, I did not! It is better to get that tested. Right?"

"Of course. By the way, we will be getting vaccinated soon!"

"Yeah, I got an email saying that we can get vaccinated in a week or so"

"Me too!"

"Well first one is just make your B cells to wake up. We will be protected only after a week of the second dose, the booster shot. That would be a month from now."

"Later is better than never"

"Of course. I hear lots of people do not want to get vaccinated. People working in the nursing home in OHIO  dont want to get vaccinated. I wonder why?"

"I dont know, It is crazy"

"We will be getting pfizer vaccine, I believe"

"Yes! mRNA of the spike protein huh"

"So, it will get translated to spike protein in our ribosome?"

"Yep. Our B cells will start making antibodies against the spike proteins. Those antibodies will fight against the corona virus which has spike protein on it"

"Why cant we inject spike protein itself?  Why m-RNA of spike protein?"

"I really dont know. You need to look it up!" 

"I love biology. It is sexier than your ass, Caro!

"Ha ha ha. You can only marry my ass. Not the biology, no matter how sexy it is"

"Anyway I tried to look it up, but could not find any answers for why cant they use spike protein itself as the vaccine"

"Seems like nobody is as crazy as you are. Only you care about all these"

"Hi I care about your ass too!"

"That's selfish too"

"WHY?"

"Because if I am happy, you would be happy too!"

 "Can I come over there to your place"

"What if I say "No! you cant come now" Will you listen?"

"I will come anyway. I wont listen to what your mouth says.  I know what your heart says"

"lol, Then why do you ask my permission?"

"Idk, I just want to tell you that"

"I like surprises"

"OK, I will be there soon"

***************

"Oh my God Caro! Where did you get this!"

"I got it from Vani"

"Who is she?"

"Another Indian girl. Suneeta introduced her to  me. She is nice"

"Is this her Saree?"

"Yes. She said I can have it for free"

"Really? Not wearing any blouse? Tops?"

"Ha ha ha Just  bra"

"Do you wear petticoat  under the Saree?"

"Of course, she gave that with the Saree"

"Panties?"

"Ha ha ha, You need to find that out!"

"You can not go out like that topless"

"I m not going out. It is just for you"

"You are crazy"

"How do I look?"

"I cant say. Do one thing, Let me take a photo with Saree on. And take one another after you take off all your clothes so that I can compare both and tell you which one looks better?"

"Lol. With Saree and a naked photo? You want to compare my look?!"

"Yes!"

"Can you close your eyes and take that photo?"

"Thats impossible!"

"I wont let you then"

"Come here! My God, you look beautiful darling!"

"Marry me, then!"

"Let us get married once you become pregnant!"

"I really don't care"

"What if I dump you once you become pregnant?"

"That's my problem. Right?"

"I hear that once we get married we wont be attracted to each other anymore"

"Thats bullshit"

"I heard that"

"Let us get that tested then"

"Test what?"

"Whether you fuck me less or more after you marry me?"

"What would be your guess"

"I will say, NO every day so that you will rape me?"

"Why?"

"I dont know. I want to get raped by you"

"Are you all right? I think your hormones are up regulated"

"How would you test that?"

"Let me kiss you first?"

"Where?"

"Hold on darling! In your neck, cheek, lips"

" And?"

"I thought you like surprises"

"Yes"

-to be continued.




Wednesday, November 11, 2020

மீ டூ காலம்! என்னடி எப்படி இருக்க? (40)

இக்கரைக்கு அக்கரைப் பச்சை னு சொல்லுவாங்க. அமெரிக்கா வந்த புதிதில் எல்லாமே நல்லாத் தெரியும். புதுக் காதலி மாதிரி. 

நம்ம ராசி அப்படி. இந்த நாட்டுக்கு குடிபுகுந்ததும், இந்த நாடு நம்ம நாடு மாதிரி ஆயிடுச்சு. பாலிடிக்ஸ கவனிக்காமல் இருந்தபோது ஒன்னும் பெருசா தெரியவில்லை. கவனிக்க கவனிக்கத்தான் இந்த நாடு பத்தி புரிய ஆரம்பிக்கிது.

அமெரிக்காவிலேயே குப்பை கொட்டும்போது நம்ம ஊர் பரவாயில்லைனு தோனும். ஆனால் அங்கே போய் பார்த்தால் அடடா இவர்களும் பலவகையில் ரொம்பவே "முன்னேறிட்டாங்க", அமெரிக்கா பரவாயில்லைனு தோனும்.

 எலக்சன் முடிவு என்ன?

வெற்றி பெற தேவையான எலக்டோரல் வோட்ஸ் (270)

 

 

 

 

Joe Biden
290
 
 
Donald Trump
214

 

 ஜியார்ஜியா (16)வும் பைடன்க்குத்தான் போய் சேரும் போல. ஆக ட்ரம்ப்க்கு ஒரே வழி, எலக்சன் ஃப்ராட்டுனு ஆரம்பிச்சு கலகத்தை தூண்டிவிட்டு எழவைக் கூட்டுவது ஒண்ணுதான்.

அதைத்தான் இப்போ ரிபப்ளிக்கன் பார்ட்டி செய்து கொண்டு இருக்கு. :)

-----------------------------------

 "It is funny, We used to laugh at everybody but now everyone is laughing at our political drama, Caro"

"Yeah, it is fucking crazy!"

"Hey, mind your words, Caro!"

"Why? Is that because I am a girl? I should not use f-word?"

"You can be polite"

"Not when everything is getting fucked up like this"

 "Hey! You look sexy when you are mad!"

"Really?"

"lol"

"You lied right? Cheap bastard"

"I did not.  Anyway I dont think he will leave the office. There is no law says loser has to leave the office. They expected the loser will leave on his/her own"

"I dont think he will leave even if after second term!"

"lol"

"I am serious. He likes the power. Lots of people do"

"I am different. I like to be submissive"

"You are not"

"Especially in bed"

"I would love that"

"Did you hear about Pfizer/BioNtech vaccine for Coronavirus,?"

"90% efficacy they say?'

"Is that true?"

"They can't lie about it"

"Is that too good for a vaccine?

"Of course it is very good"

"How does this work?"

 Frontiers | Serological Approaches for COVID-19: Epidemiologic Perspective  on Surveillance and Control | Immunology

 "We have to target the virus and get rid of it. Right?"

"Yeah, how do we do that?"

"Do you know what is an epitope?"

"A protein present in the surface of a pathogen like virus. Right?"

"Yeah, antibodies synthesized by our B cells usually binds on one or more epitopes, once antibodies bind on them, then the cells will find a way to kill the pathogen which has the epitope" 

"So, this spike protein or whatever is an epitope?"

"Yes. Now we need to make receptor molecules/proteins on the surface of our immune cells, at which the epitope (spike protein) of the virus (pathogen) would love to bind on"

"The antibodies are on the surface of an immune cell like B cell? Correct?"

"Yes the antibodies are proteins they can bind on the epitope of pathogens (virus/bacteria). They usually present in the surface of the B cells (an  immune cell).

 

 Adaptive immunity | Immune response (article) | Khan Academy

 

 

 

https://s3-us-west-2.amazonaws.com/courses-images/wp-content/uploads/sites/1094/2016/11/03172844/OSC_Microbio_20_01_Epitope.jpg


"So How do we make the antibodies?"

"You need to trigger the B-cell to make antibodies. That is what the vaccine is all about"

"How are we going to trigger, Caro?" 

"We will deliver a messenger RNA  which can get translated to the spike protein (epitope) by using nanoparticle-vehicle but these spike proteins which will be made from mRNA are not on the virus. We do not provide the virus itself, we only provide the ingredients (mRNA) to make spike protein (epitope) and so it is harmless to our body.Once B cells in our body recognize the spike protein, it would like to get rid of the spike protein, who is a "foreigner". So it will make an antibody for targeting the spike protein and it will be placed on the surface of the B-cell. Now, the spike protein will come and bind on the antibody. and B-cell will find a way to get rid of that spike protein"

Delivering mRNA by shocking lipid nanoparticle to fuse with cancer cells |  by Shamit Shrivastava | Medium

 

"So, now our B-cells are able to recognize the spike protein which is on Virus?"

"Exactly. B-cells with the help of helper T-cells will make the antibodies for the spike protein and will be waiting for more spike protein to come and bind on them. Now if the virus enters our body and tries to invade our cells using the spike protein (the epitope) bidning, it will be killed by our immune B cells"

 

 

"So the vaccine is just m-RNA of spike protein?"

"Yes"

"The mRNA will be supplied as such or it will be incorporated in some cells?"

"I really don't know. I believe you can just provide the m-RNA." 

"It was a long lecture, Caro! Thank you!"

"That's not enough"

"What do you want?"

"Can you be my slave tonight?"

"Just a slave or sex slave?"

"The latter"

"You are joking, right?"

"I am not!"

"Fuck you Caro!"

"Any time!"

-to be continued

Relax please!