Showing posts with label vaccine. Show all posts
Showing posts with label vaccine. Show all posts

Friday, April 16, 2021

மீ டூ காலம்! என்னடி எப்படி இருக்க? (53)

 கொரோனா வைரஸ் ஸ்டேட்டஸ் இந்தியா!

எதிர் பார்த்தது போலவே, இந்தியாவில் சக்கண்ட் வேவ் முதல் அலையைவிட பெரிதாகத்தான் இருக்கு. உயிரிழப்பு கம்மியா இருப்பதுபோல் தெரிகிறது. எனக்கென்னவோ ஒரு வழியா எல்லா நாட்டிலுமே ஒரே முடிவுக்குத்தான் வர்ராங்க. எத்தனை நாளைக்குத்தான் பயந்து பயந்து வாழ்றது? அன்லக்கி னா சாகிறான். நம்ம லக்கி.

இந்த கொரோனா வைரஸ் காலத்தில் அப்பப்போ ஏதாவது எழுதிட்டுப் போறது நல்லது. இல்லைனா இவனும் சமாதியாயிட்டான்னு முடிவுக்கு வந்திடுவானுக. ஆனால் ஒண்ணு நான் எல்லாம் செத்தால் அவன் அவன் கொண்டாடுவானுக! :)

------------------------

"Hi Caro!"

"Tell me"

"Did I ever tell you, why I love you so much?"

"Ha ha ha Why?"

"It is not because you are beautiful"

"ha ha ha. So I am beautiful?""

"Listen bitch! It is not that you have a sexy ass"

"Go on, I am listening"

"You dont talk nonsense like other girls do"

"Like what?"

"You know when girls are in love and their hormones are up, they talk lot of trash. Worse than a drunkard"

"Suneeeta?"

"No, leave her alone, darling. In general, girls are like that. Then after sometime, they will ask the same person with whom they thought they were madly in love, "Who the fuck are you?"

"I dont think so"

"Hey, they do. You dont need to defend every girl's bullshit.  OK?"

"Of course, I won't"

"I am not going to defend all men either. Every fucking man is different. So are every fucking girl. Just because you and her has a pussy, you dont need to defend every fucking girl in the world"

"OMG, Are you ok?"

"I dont know. May be I want you to hate me"

"Well, I will try"

"It is easy"

"How?"

"I will tell you later. Check this out, Sowmya gave me a ride"

"Really?"

"Yeah I was walking out of Starbucks, and she was just getting on in her car and she gave me a ride"

"You did not drive there?"

"No, it is just couple of miles away from my home, I just walked there. So, she offered me a ride"

"I wonder why?"

"She has bought a new BMW. A big one"

"Ha ha ha"

"I think she wanted to show me her car and that she wanted to tell me that she could afford such a big luxury car"

"She gave you a ride because of that?"

"You know people are funny. Just being rich never makes anybody happy. They have got to show others that they are rich. Only that makes them happy"

"Really?"

"I am serious Caro! Thats what makes her happy"

 

https://upload.wikimedia.org/wikipedia/commons/thumb/e/e4/2019_BMW_330e_M_Sport.jpg/280px-2019_BMW_330e_M_Sport.jpg 

 "You could afford one too. I mean if you prioritize that. You can afford a BMW or a Mercedes"

"Well, I am not going to buy one. It is just waste of money. And then I dont want to give ride others either"

" I dont believe your theory though"

"It is very normal Caro. People want to show others what they can afford and what they are capable of. Thats what make them happy"

"I dont know"

"Only silly things make big people happy"

"Anything wrong with that?"

"I dont know. It does not matter to me what she can afford. Well, I am worse than her"

"Why?"

"I did not ask anything about her new car?"

"YOU DID NOT?" 

"I talked about other things during the ride and said thank you after the ride"

"You think she was upset?"

"Probably. She may have thought that I was rude or discourteous"

"May be you are"

"People are silly, Caro. I am becoming very very selfish these day"

"Well, how so?"

"Idk, probably I am becoming sadistic"

"Was that sadistic?"

"Of course. I think I was impolite but she cant complain"

"So, you are telling me, she gave you a ride to just show her car"

"Yes, that is what I am telling. Who needed a fucking ride anyway? I will be happier walking home in this nice weather"

"Then, why did you accept?"

"Yeah, I should have said that I dont need a ride"

"You could have been nicer"

"How?"

"You could have said that it was a nice car"

"I told you, I am becoming sadistic these days"

"You are nice to me."

"Idk how long that is going to last"

"For ever"

"Hi, why do people get blood clot when they get vaccinated?"

"J and J vaccine?"

"Yeah, the Astrazneca vaccine has similar problems as well"

"We got Pfizer vaccine"

"So, mRNA does not precipitate but the adeno viruses precipitate out in our blood?"

"It is one in million or something. Right?"

"They paused J &J vaccine in US now! Idk how many people will be ready to take it if they restart"

"Men dont have such problem. Right?"

"Yeah, may be they should give this J&J vaccine to men only. These fucking idiots cant think. They could have continued J &J just vaccinating men"

"No men had issues?"

"Not this blood clot problems. Only women have had issues"

 - to be continued

Relax please




Tuesday, February 16, 2021

மீ டூ காலம்! என்னடி எப்படி இருக்க? (50)

Corona virus in India! Big mistake!

Indians seem to think, it is all over and that we outfought the virus! Not many cases around us, they say! People are making fun if someone is wearing a mask!!

The problem is..

It happened in Italy, Spain. It went up and came down for few months. After a break the second infection started much more aggressively. It killed much more people than people got killed during the first infection.

Same thing happened in France!

Same thing happened in USA!

Same thing  happened in UK! 

Germany, Russia! 

That's the trend we saw. 

India is not an exception to that?!

People in India "overlooking" that. Reason could be for survival. It is hard to shut down everything and live. It is impossible? If that is the case, I understand.

If you think that it is over. Then you are making a big mistake!

It is quite possible India will have a HUGE number of cases and DEATHS soon. I wish I am wrong!

It is your life! Live happily or die "bravely"!

Who am I to advise you to live or die?!! Yeah, it is your life!

--------------------------------

"என்னடி கரோ! எப்படி இருக்க?"

"போடா!"

"What?"

"Ha ha ha"

" How did you learn Tamil, bitch?"

 "Vani taught me"

"That bitch!"

"Dont call everyone as bitch. Your bitch is just me" 

" What else she taught you?"

"She taught me how to keep love life interesting"

"How is that?"

 "I cant reveal everything to you. It is between girls."

"You talk about sex with her?"

"Ha ha ha"

"I can never talk about sex with another guy. It is impossible"

"Really?!! Why?"

"I dont know. Is that weird?"

I dont know. Probably not"

"What did she taught you?" 

"She explained me why Indian marriages are not breaking and such"

"Ha Ha ha. Thats funny"

"It is not"

"That was history, Caro. WAKE UP!  It is all fucked up now!"

"Really?" 

" Today, everything got fucked up in India. Once women got financial independence in India, Indian marriages are fragile. Women want to be fooling around, drink, smoke just like fucking men. "

"Why?"

"They earned their financial freedom you see! They try making a good contribution to fuck up the Indian culture. Honestly marrying a white chick would be better than marrying a half-baked Indian bimbo"

"Oh, that's why you are behind my ass?"

"Of course, now you have got a reason for dumping me?"

"Fuck you!"

"I have a question"

"About Vani?"

"No, it is about biology"

"What?"

"Lately there is a conspiracy theory that Covid-19 is a man-made virus"

"Ha Ha Ha Made in China. Right?"

"The chinese say it was made in USA. Let us not worry about that. How do you make a virus in the lab?"

"Good question!"

"I want answer bitch!"

"I really dont know whether they will make it from a scratch or mutate another virus"

"I tried to look it up. It is unclear to me"

"I think they try to introduce few harmful genes in a virus"

"I see. Let us see the russian vaccine Sputnik V"

"Sputnik V?"

"Did you know the Russian vaccine works well and people in the west now accepting that Russian did not lie about it?"

"Really?"

"There was an article in British journal or something?"

"Who said that?"

"READ THIS!"

The Russian coronavirus vaccine, Sputnik V, was 92 percent effective at preventing symptomatic illness in a large clinical trial, robust protection that puts it in line with top vaccines developed in the United States and Europe, according to results published in a peer-reviewed journal Tuesday.

 "So? It works?"

"Thats what the experts say now!"

"It really does work?"

"Yes, it does Caro! Any way, let me get to the point. You know Sputnik vaccine has AD-23 and ADS and both of them are harmless viruses"

"Right?"

"They added the gene which can make the spike protein of Covid-19 into the genome of AD-23 and ADS" 

"So?"

"OK, Can I say,  AD-23 and ADS are now genetically modified viruses? Does it make any sense?"

"It does"

"The same strategy can be used to make new "Covid-19"!"

'Nobody has any proof supporting that man-made virus claim"

"Idk, some people believe it was made in China. Some scientist from west believe"

"It does not matter. We have to get the vaccine and we got"

"Did you get your second dose of pfizer vaccine?"

"Tomorrow"

"You might get mild fever?"

"Did you get?"

"No, I did not. My upper arm was sore, thats all"

"Then why would I get fever for the second dose?"

"Most of the people get fever, Caro"

"Why did not you get?"

"You know what? I strongly believe I got infected by Covid-19 in the very beginning itself?"

"When?"

"I think this virus was around from Jan 2020. We started realizing only in the beginning of March 2020"

"If you were infected already?"

"If I was infected by this virus already, my immune system already dealt with spike protein and it is not new to my immune system. So, Vaccine might not have a huge effect"

"Idk, it is hard to say"

"Indians claim they achieved herd immunity"

"Really? Is it possible?"

"I think it is quite possible. It is hard to control the spread of virus in India They are trying to justify why they have less cases unlike west"

"So ? Indian has achieved herd immunity?"

"Idk, Caro. We have to wait and see.It is puzzling to me. No matter what, we cant do anything about it."

"Right!"

"Why dont you invite the chick, Vani?"

"Why?"

"I want to tell her not to lie to you about how great Indian culture is"

"So? You want to take her on, and harass her?"

"NO! I just want to open her eyes and  see the world"

"No, I am not going to introduce her to you!"

"Why?"

"Because you may annoy her and she will break up my friendship"

"Come on!"

-to be continued


Relax please


Friday, January 22, 2021

மீ டூ காலம்! என்னடி எப்படி இருக்க? (49)

இந்தியாவின் கோவாக்சின்!

நான் நினைத்ததுபோல் அல்லாமல் இந்தியாவும் ஒரு கொரோனா வைரஸ் வாக்சின் தயாரிச்சு, வெளியிட தயாராகியுள்ளார்கள்.

 இந்தியன் வாக்சின் எப்படி இந்த வைரஸ்க்கு எதிரா வேலை செய்யுது. இல்லைனா வைரஸ்க்கு எதிரா எப்படி எதிர்ப்பு சக்தி உண்டாக்குது?

 இது   ஃபைசர், மெடொர்னா மாதிரி m-RNA  டெக்னாலஜியா?

இல்லை!

இது ரஸ்யாவின் ஸ்பட்னிக் அல்லது  ஆக்ஸ்ஃபோர்ட் வாக்சின் போல ஸ்பைக் ப்ரோட்டீன் சுமந்து வரும் அடினோவைரஸ் டெக்னாலஜியா?

இல்லை!

கோவாக்சின் என்ன பயோ டெக்னாலஜி வகையை சேர்ந்தது?

சைனாவில் தயாரித்த வாக்சின் போன்றது. அதாவது வீரியமில்லாத (கொல்லப்பட்ட) கொரோனா வைரஸ்தான் இந்த வாக்சின். வைரஸ்  கொல்லப்பட்டு இருந்தாலும், அதில் உள்ள பயோ மாலிக்கூல் (ஸ்பைக் ப்ரோட்டீன் உள்பட) எல்லாம் உயிரோட இருக்கலாம். அதை நம் உடலில் செலுத்தும்போது, அதற்கு எதிர்ப்பு சக்தி உண்டாகும்..

 பி பி சி ல இருந்து எடுக்கப்பட்டது கீழே

How does Covaxin work?

The homegrown government-backed vaccine has been developed by Bharat Biotech, a 24-year-old vaccine maker, which has a portfolio of 16 vaccines and exports to 123 countries.

It is an inactivated vaccine which means that it is made up of killed coronaviruses, making it safe to be injected into the body. Bharat Biotech used a sample of the coronavirus, isolated by India's National Institute of Virology.

When administered, immune cells can still recognise the dead virus, prompting the immune system to make antibodies against the pandemic virus.

A Covaxin vaccine vial 

 

The two doses are given four weeks apart. The vaccine can be stored at 2C to 8C.

Bharat Biotech says it has a stockpile of 20 million doses of Covaxin, and is aiming to make 700 million doses out of its four facilities in two cities by the end of the year. 

 

What is the controversy around Covaxin?

It all began when the regulator said the vaccine had been approved for "restricted use in emergency situations in public interest as an abundant precaution, in clinical trial mode, especially in the context of infection by mutant strains".

Experts wondered how a vaccine was cleared for emergency use by millions of vulnerable people when its trials were still underway.

Both the manufacturer and drug regulator say Covaxin is "safe and provides a robust immune response".

But the All India Drug Action Network said it was "baffled to understand the scientific logic" to approve "an incompletely studied vaccine". It said that there were "intense concerns arising from the absence of the efficacy data".

Bharat Biotech has defended the approval, saying Indian clinical trial laws allowed "accelerated" authorisation for use of drugs after the second phase of trials for "unmet medical needs of serious and life-threatening diseases in the country". It has promised to provide efficacy data for the vaccine by February. 

 

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 கதைக்கு தாவுவோம்!

 "You want to taste Cyanide and live?!"

"Live? You mean die!!"

"Of course you can live, Caro!"

"Really? How?'

"You can take very little Cyanide ion (CN-), not in the form or sodium or potassium cyanide (Na+  -CN or K+  -CN) but in a different form, and live"

"How can I do that?"

"Have you ever eaten apple seeds while eating apple?"

"Not really"

"Very careful, huh?"

 "Ha ha ha"

"It tastes somewhat bitter.I have eaten apple seeds."

"Seriously?"

"YES, It is ok to eat few seeds. Apple seeds have a compound which releases cyanide ion slowly"

"Slowly?"

"Yeah, it is an Organic compound with a CN group in it,  which can degrade in our stomach (you have HCl there), and release -CN ion"

"It wont kill me?"

"It releases very little amount of cyanide, not like KCN or NaCN or HCN. If you eat grams of apple seed, then only cyanide can kill you! Thats very unlikely"

"It can really kill me if I eat a lot of apple seeds"

"YES,  IT WILL, Caro!"

"How does cyanide ion kill us, anyway?"

"I think it sort of making strong complex with Fe2+ ion in hemoglobin, where usually oxygen binds and CN, does not allow oxygen to bind on it. Carbon monoxide does the same. So, Hemoglobin can not carry oxygen to our cells because cyanide took the spot of Oxygen and, so cells will not live without oxygen. When our cells die, we will die too"

"Seriously?"

"I strongly believe that is how it kills us. You must have studied, Right?"

"I don't study like Chemists do" 

"Anyway, Cyanide ion is the one which causes trouble. You can get that in several different sources. It is all about love"

"Ha ha ha, love?"

"Yeah, Fe2+ ion in our Hemoglobin loves Cyanide ion more than Oxygen molecule. And they form a strong bond and so, poor oxygen can not bind. That eventually kills us"

"What do we got in Apple seeds you said?" 

"It is called Amygdalin. It has couple of glucose molecules and a cyanide group as well"

"Hmm"

"Hmm what?"

 Amygdalin - Molecule of the Month - November 2017 (HTML version)

"You are weird. "

"I am not."

 "Why do you do such research now?"

 "Learning about anything is always good, Caro. Especially when we have the background to learn. Anyway, that is what really happening. Do you know bitter Almond is bad for you if you eat a lot?"

"What does it has?"

"Hydrogen cyanide, they say. Actually it also has Amygdalin which generates the -CN, just like apple seeds"

 

Bitter and Sweet Almonds | Download Scientific Diagram

 ********************

"Shall we talk about living?"

"OK, Darling. Do you know, Phillip Rivers?"

"The Charger's Quarter back?"

"He was with Chargers. He recently played for Indianapolis Colts"

"What about him?"

"He is retiring."

"Good for him"

" You know how many children he has?"

"How many?"

"Nine!"

"Seriously"

"He has a beautiful family"

https://static.clubs.nfl.com/image/private/t_landscape_tablet/chargers/tzrdejdpc5rh5itfabh9.jpg


 "It is indeed a beautiful family"

******************

"Did you get your shot? The PFIZER vaccine?"

"Yeah! I did"

"How did you feel? Any fever?"

"It was kind of mildly sore in my arm. I did not get any fever though"

"Me neither but the second dose will give you mild fever"

"Really?. Is that a larger amount of mRNA?"

"Apparently not. It is exactly same amount of same dose . 0.3 mL of that solution, but Idk the concentration of mRNA. I think our immune system is already awake because of first dose. Now the second dose will make it to fight hard,which might give you a mild fever"

"I dont want fever"

"It will be very mild, Caro. Dont worry"

"Do you know anything about this Chinese vaccine?"

"I think it has inactive or killed virus in it"

"Really?"

"Thats what I heard. They try wake up our immune system by providing weak virus" 

"I think mRNA vaccine is the best!"

"I dont think so. I think Astrazeneca - oxford vaccine is better for practical purposes and it is cheap. Countries like India  can easily afford"

"They say it is 60-92% effective. Such a wide range!"

"I would take it as 60% effective."

"Well"

"What do we know about Johnson and Johnson vaccine?"

 "I just heard, some segment of DNA of viral genome is inserted in Adenovirus 26,"

"Is that similar to sputnik and oxford vaccine?"

"I need to compare and see the difference. But this vaccine you need only one dose"

"Are they ready for FDA approval?'

"I think they are in the final stage of phase 3 trial May be it will be approved in few months?"

-to be continued

Relax please





Wednesday, December 30, 2020

மீ டூ காலம்! என்னடி எப்படி இருக்க? (45)

Breaking News! US Republican congressman Luke Letlow dies of Covid-19 complications. He was 41 year old. He was tested positive 10 days ago. Moved to ICU a week ago. Today he died. He was a healthy 41-year old man! He had a wife and two beautiful children.

Louisiana congressman-elect Luke Letlow dead from COVID

This is why this virus is scary!

Trump and Republicans never forced people to wear mask and did not avoid big rallies. Well, some never learn no matter what happens.

=======================

Astrazeneca-Oxford vaccine approved today in UK! 

May be, before the end of this week, UK people will get vaccinated. India would approve that as soon as UK did.

This vaccine is based on Adenovirus, not based on mRNA. Thats appropriate for India because it is more stable. 

mRNA or any RNA are highly unstable macromolecules. DNA is much more stable than RNA because it lacks a 2-prime hydroxyl group. What? What is that? RNA has a sugar called ribose which has a OH group at 2-prime position. But DNA does not have that. It has 2-prime deoxy ribose. The lack of 2-prime OH group  gives lot of stability to DNA. To understand what I am saying you need to know, chemistry, biochemistry and biology as well.

I suspect even paappaan nanthavanathaan  would understand because biologists lack basic chemistry knowledge. Especially biologists in India. Who the fuck he is? Dont worry! A sneaky paappaan! Living in US as a "slave" under the beef-eating bosses  

If you do not have that background it is hard for you to follow what I am saying here. Hold on! That does not make you inferior or anything like that. It is not your area. You may be coding and making big bucks! Life is all about how much fucking money you make. Right?

Now, Dont think paappaan Sujatha or Kamal haasan can understand what I am talking about (DNA vs RNA stability etc)  though they/you might claim that they are geniuses. They can not understand that either. Get that in your fucking dead brain! One need to have some biology and chemistry  background to understand some things.

Any way, mRNA are highly unstable and so Pfizer vaccine and moderna vaccine are unstable and need to be stored at dry-ice (-78 C) temperature to avoid decomposition. Thats a big problem for countries like India. Sputnik and Oxford vaccines are not based on mRNA and so they are much more stable. They can be stored at -20C or so. So it can be transported and stored easily. These two are more appropriate for Indian conditions! 

 The bad thing in India is that only rich can afford  this vaccine. Just like by-pass surgery, only rich can afford. But in western nations, almost all citizens are treated equally and can get vaccinated because it is free! It is not really free. They take the tax payers money and use for that! இதுதான் மேலை நாடுகளூக்கும் நமக்கும் உள்ள வித்தியாசம். As MR Radha says, ithu ungka thalai yezhuththu!

இந்தியா இந்தியானு பெருமை பேசுற பார்ப்பானுகளூக்கு நான் சொல்ல வர்ரது என்னனா. இதுதான் உங்க நிலைமை. நீ உலகத்திலேயே அறிவாளினு நெனச்சா, இதுபோல் ஒரு சூழலில் அதைக் காட்டனும். எப்படி? மேலை நாடுகள் கண்டு பிடிக்கும் முன்னால நீயும் ஒரு வாக்சினோட வந்து நின்னு இருக்கனும். அது உன்னால முடியலைனு உனக்குப் புரியனும். ஆனா இதெல்லாம் உன் மரமண்டையில் ஏறாது. இருந்தும் ஏன் சொல்றன்னா நம்ம ஊரில் பார்ப்பானுக்கு  உருவிவிடும் திராவிட கைக்கூலிகள் திருந்தனும்.

 இதிலே என்ன அதிசயம்னா, சைனா கூட ஃபைசர் வாக்சின் வாங்கி பயன் படுத்துறாங்க!! ஜப்பான் மற்றும் பல மேலை நாடுகள்கூட. அமெரிக்கா ஏன் தன்னை உலகிலேயே தலை சிறந்த நாடுனு சொல்லிக்கொள்கிறதுனு கேட்டால், இது போல் காரணங்கள்தான்.

ஒரு நிமிடம்! I am not bragging because I happened to live in US. All my relatives live in India just like you are!

நான் இன்னும் வாக்சின் போட்டுக்கவில்லை. அதாவது என் டேர்ன் இன்னும் வரவில்லை. அனேகமாக இன்னும் ரெண்டு மாதம் ஆகலாம். இந்தியாவில் உள்ள பணம் படைத்தவர்கள், எனக்கு முன்னாலேயே ஆஸ்ட்ரா ஜெனெகா அல்லது ஸ்பட்னிக் வாக்சின் எடுத்துக்க வாய்ப்பிருக்கு. பண அடிப்படையில் எல்லாம் அமெரிக்காவில் வாக்சின் ப்ரையாரிட்டி கொடுக்கப் படுவதில்லை. இந்தியாவில்தான் அது போல் வசதிகள் இருக்கு! இதை எல்லாம் உங்க மரமண்டையில் ஏற்றிக் கோங்க!

The bottom line is, we could not come up with a vaccine. We depend on western scientific and medical achievements but we never accept that! I wonder why??? இதுக்கு காரணம் என்னனா ..அது இதுனு சப்பைகட்டுவானுக நாதாரிகள். வாய்க்கு மட்டும் கொறச்சல் இருக்காது.

------------------------

இந்தியா நினைவுகள்..

என்ன தம்பி எப்போ வந்தீங்க? நல்லா இருக்கீங்களா? னு விசாரிப்பார் நம்ம செல்வகுமார் அண்ணன். எந்நேரமும் போதைலதான் இருக்கும் அண்ணன். ஆனால்  மக்களின் தரம் தெரியும். நம்ம தெருப் பையன் பெரிய படிப்பு ஏதோ படிக்கிறான்னு ஒரு அன்பு மரியாதை. ஒரு பிரச்சினைனா முதல் ஆளா வந்து நிக்கும்.

உடனே இந்தியாவை மிஸ் பண்ணூறேன்னு நெனச்சுடாதீங்க. இதெல்லாம் அந்தக் காலம். இப்போ எல்லாம் எவனும் எவனைப் பத்தியும் கவலைப் படுவதில்லை. சம்மந்தா சம்மந்தம் இல்லாதவன் எல்லாம் வந்து  தெருவில் குடியிருக்கிறானுக. பூர்வீக சொத்து வச்சிருந்தவன் எல்லாம் எங்கேயோ போயிட்டான். 

கள்ளக்காதல், செல் ஃபோன் காதல் எல்லாம் மலிந்து கெடக்கு. எல்லாரும் பிசியா இருக்கானுக. உக்காந்து ஊர் கதை பேச எவனுக்கும் நேரமில்லை. முன்னேறிட்டானுகளா இல்லை நாசமாப் போயிட்டானுகளா னு தெரியலை.

அமெரிக்கா வந்த புதிதில்..

இருந்த இடம் ஒரு காலேஜ் டவுன். தெரிந்தவன் தெரியாதவன் எல்லாம் ஹல்லோ சொல்லுவானுக. யாருனே தெரியாது, எதிர்த்தாப்பிலே பார்த்தால் ஹலோ சொல்லுவாங்க. புரியாத கல்ச்சர். என்னனு கேட்டால் எதிர்த்தாப்பிலே ஐ கான்டாக்ட் பண்ணூம்போது ஹலோ சொல்றதுனாலயோ, ஹவ் ஆர் யு டூயிங் திஸ் மார்னிங் னு கேட்பதில் ஒன்னும் பெரிய தப்பில்லைனு சொல்லுவாங்க. உடனே அமெரிக்காவில் எல்லாரும் இப்படினு நெனச்சுடாதீங்க. 

இன்று

சைட் வாக்ல நடக்கும்போது மாஸ்க் போட்டிருந்தாலும் எதிர்த்தாப்பிலே எவனாவது வந்தா.. நம்ம எதிரி வர்ரான்னு சைட் வாக்கை விட்டு இறங்கிப் போவேன்.  

மாஸ்க் போட்டு இருப்பதால் எதிர்ப்பாலே வர்ரவன் முறைக்கிறானா இல்லை புன்னகைக்கிறானா?னு பலருக்கு புரிவதில்லை.

ஆக இந்த வைரஸ், மனிதனுக்கு நல்ல பாடம் புகட்டி இருக்கு!

-----------------------------

"Caro! This virus is already started getting mutated to another strain it seems! I think the mutant is now everywhere already"

"I think it is normal. Viruses get mutated easily"

"Why is that?"

"What they say is, viruses replicates faster. As they are rushing their replication, it is easy to make mistakes and those mistakes cause mutation and so easily get mutated"

"Hmm. Are you making up this story, Caro?"

"No! It is true. Here is a reference for you in PLOS, check this out!  https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000003"

"Tell me what is in it?"

"This is what they say "RNA viruses have high mutation rates—up to a million times higher than their hosts—and these high rates are correlated with enhanced virulence and evolvability, traits considered beneficial for viruses." blah blah"

"It is beneficial for the viruses? Meaning it is bad of us?"

"Of course, they mutate for better survival. More they survive, more trouble for us. So they can kill us easily"

"This virus must be formed from another virus? A mutant of another virus. Right?"

"Of course. Covid19 did not come from nowhere. It should be a mutant of another virus. They say, its "parents" of covid 19 used to attack "bats". Now after some mutation, the daughters namely coronavirus-2, a mutant form of bat virus started attacking human cells. They are everywhere in the planet."

"Can't they make a bad mutation that will lead to their extinct? In other words the mutant version is less harmful to us? Our cells can kill them easily?"

"It is possible but usually the mutant will have better survival rate. Some mutant might not survive. Such mutant viruses die easily and so we dont even notice them.  The surviving ones are stronger. Meaning, they can kill our cells easily"

"Explain me what is a mutation, Caro? What is an original covid-19 and what is a mutated covid-19"

"That is your area You explain me"

"Mutation is my area? My area is your ass only!"

"Lol. Too bad, you cant publish that research anywhere"

"OK,  Let us say, spike protein of covid-19 has M-A-D-Y-W-R---------P-E-S as amino acid sequence. Mutant spike protein sequence would be M-A-D-Y-W-R---------P-V-S. Glutamate (E) is changed to a Valine (V) in the mutated virus.

"You know one-letter code for all amino acids?! What is an A?"

"Caro's ass!"

"lol"

"Fuck you, Caro! Are you checking my on amino acids knowledge?"

"Answer my question, mister!"

"Alanine, bitch"

"What is P?"

"P is Caro's Panties"

"lol, I thought you would say something else"

"OK, P is proline"

"How about B?'

"No amino acid has B, bitch!"

"How about "O"?

"Ornithine?"

"Is that an Amino acid?"

"Of course. Go, read Urea cycle again"

"But that is not in the Proteins"

"So what? Ornithine is a natural amino acid. Very analogous to Lysine"

"I dont think Ornithine has one letter code as "O"?"

"Why? no white man named it, Right? Fucking whites!"

"lol"

"3-Hydroxy and 4-hydroxy Prolines are all in Proteins like Collagen. But they do not have one-letter code either"

"True"

"Some white guy has to address that issue too. Then only this fucking world would listen"

"Are you better than whites?"

"Of course"

"You are better in bed I know, but  not in everything"

"Anyway,  A-D-Y-W-R---------P-E-S is the amino acid sequence in Spike Protein. What is the codon for Tryptophan?"

"Have you memorized that too?"

"No, not yet. I have to look it up"

"Good. You make me feel better now"

"Hey I was teaching this student, chemistry"

"Girl or guy?"

"It is a guy! How does it matter?"

"It does to me"

"Anyway, he had problem figuring out the Electronegativity trend in periodic table. I said, You have to start from F, fluorine. That's the most electronegative atom in the periodic table. You can go only one way from there in the periodic table, it will have to decrease whether you go the left or down in the periodic table"

"I see. Start from Fluorine, huh?"

"I told him, Always remember, you have got to start from F like in Fucking! He was laughing for ever! Even now, when I text him for something, he will say I will never forget Fluorine is the most electronegative atom. F like in Fucking!"

"That's hilarious"

"Now he knows how to see the trend of electronegativity in a periodic table. That's the whole point"

"Dont tell that to girls"

"I can tell that to only one girl, namely Caro!"

"Do you flirt with them? The girls you teach?"

"I dont know. You should ask them"

"What's her name? You taught her organic chemistry? A premed student or something?"

"That was Fatima! A muslim girl"

"I thought they are very sensitive. You need to be extra careful with them?"

"Idk, I correlate chemistry with real life so that they can remember easily"

"Like what?"

"It was funny. I was teaching kinetic control and thermodynamic control to his girl, Fatima. But She was keep asking me how to remember that..blah blah I told her, OK, Kinetic control is like one has a crush on someone. One is attracted to him or her. It is very quick decision, it is fast but most of the time it wont last long. It is like a short-term relationship . Thermodynamic control is like you interact, get to know that person, there are ups and downs in the relationship. and finally decide that that guy is worth marrying and you go on with a long-term relationship"

"What did she say?'

"She was giving me sarcastic look and said, I GET IT now with a smile"

" Then?"

"I was not sure whether that was an appropriate correlation but sometimes I do that"

"Did she continue the sessions with you, afterwards"

"Of course. I taught her orgo 1 and orgo 2 as well. She got an A in both of them. She may be in medical school now"

"Was she bright?"

"Of course. She was a bright student"

"She is from middle east?"

"Yes, her parents are from middle east and they kind of settled here in US"

"How did you come to know her?"

"Her mom contacted me through online tutoring site. She was telling me that her daughter has difficulties with orgo and she is very bright blah blah. I said, let me see. Let me talk to her. She said that she prefers to meet in a common place like library or starbucks. I said, OK"

"You said she was bright"

"Not all bright students can study organic chemistry. Lot of bright students will have difficulties because it is different kind of subject. Bright students wont like it"

"Seriously? Was she cute?"

"I really dont care, Caro. What matters most is her learning style. If it clicks well, look hardly matters. A not-so-good-looking girl will look beautiful if she appreciates and understands what I teach her"

"Really?"

"I tried to teach couple of kids,who are my friends' friends' daughters or sons.It never clicked with them"

"What do you mean?"

"Idk, I never could have had any pleasure teaching them so far"

"Because?"

"They dont catch the important points I teach them. They answer in a weird way. Though the answers are correct, they dont please me. The point is students' look hardly matters. Neither do gender, race or language the student speaks matter"

"So, all that matters is the students learning style.  I dont believe it!"

"I know but it is true!"

"Do they say hi to you? Fatima?"

"They just move on. When they finished organic and get into medical school or whatever, they will just move on."

"Really?"

"I connect with some people through linkedin. Now we got derailed? Where were we?"

"Mutation?"

"Yeah. Where did Coronavirus come from?"

"There is a virus which infect bats and that got mutated to another virus which is attacking humans now!"

"Mutation is everything?!"

"Thats how we evolved. Right? The more I read, I come to the conclusion that it is hard to control the natural selection. One virus can erase us ALL! We are nothing. Why are we having all this ego??!"

"Ignorance!"

"Come here"

"Yes?"

"You smell good, Caro!"

"OMG! You are smelling my neck and arm pit. I think your hormones are up regulated"

"You smell good darling"

"Really?"

"Yeah, mine is up. How about your hormones level now?'

"Kiss me, you would know from my response!"

"Where?"

"In my cheeks"

"Why? Are you wet in every tasty spots?" 

"Ha ha ha  Probably"

"I can tell your hormones level only by tasting your saliva"

"Ha ha ha Really?"

"The taste of your saliva tells me your hormone level"

"So, you want to kiss me in my mouth or you want me to spit in your mouth?"

"Both works with me! It works better if I lick your tongue"

 "What are you really?"

"Why?"

"You know how to make a woman come without even touching them"

"You also know how to turn me on by complimenting like this, darling"

-to be continued

 




Wednesday, December 9, 2020

மீ டூ காலம்! என்னடி எப்படி இருக்க? (42)

யு கே ல ஃபைசர் வாக்சின் அப்ரூவ் ஆகிவிட்டது! 

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

 

 அமெரிக்காவும், ஈரோப்பியன் யூனியனும் இன்னும் அப்ரூவ் செய்யவில்லை! என்னைக் கேட்டால் நிச்சயம் அப்ரூவ் பண்ணத்தான் போறாங்க. எதுக்கு இந்த டிலெ னு தெரியலை.

கொரோனா வைரஸ்க்கு புதிதாக இன்னொரு வாக்சின் ரெடி ஆகிறது. Astrazeneca-oxford  வாக்சின். 

இது எம் அர் என் எ வாக்சின் இல்லை. அடினோ வைரஸ் basedனு நினைக்கிறேன். ரஷ்யா வாக்சினும் (sputnik V)  இதுவும் ஒரே வகைனு நினைக்கிறேன். 

இருந்தாலும் ரெண்டும் ஒரே டெக்னாலஜினு எங்கேயும் சொல்லக் காணோம்.

இன்னொன்னு, ரஷ்யாவில்  வாக்சின் வெளியாகி, அதை டிஸ்ட்ரிப்யூட் பண்ணிய பிறகுதான் சாவு அதிகமாகி இருக்கு? கேஸ்களும் அதிக மாகுது? என்ன வாக்சினோ என்ன எழவோ, போங்க!

 

 

 https://i0.wp.com/technewslit.com/sciencebusiness/wp-content/uploads/2020/04/Covid-19_vaccine_infographic_Oxford.png?ssl=1

 

 

அமெரிக்க எலக்சன் முடிவு ஓரளவுக்கு முடிவுக்கு வந்து விட்டது.

 

 


 
 270 to win
 
Joe Biden
306

 
 
Donald Trump
232

வாழ்க்கையில் வெற்றி தோல்வி சகஜம். அவைகளை எப்படி டீல் பண்னுறதுனு தெரியணும். ஒரு சிலருக்கு சாகும் வரை அது தெரிவதில்லை.

நீங்க முழு லூசா இருந்தாலும், உங்களுக்கு 70 மில்லியன் மக்கள் ஓட்டுப் போட தயாராயிருந்தால், உங்களை நூசுனு நிரூபிக்கிறது கஷ்டம்தான்.

-------------------------------

"Caro! Now, Astrazeneca-oxford vaccine is ready too!"

"It is unfortunate if people are dying now. The vaccine is almost ready!"

"U S death rate increased quite a bit. Almost 2.5 K people are dying everyday in US. Unbelievable! We are making a big deal out of it when 100 people were dying. Now we got used to losing people, I guess!"

" The virus lives everywhere now in host humans. "

"It is a free world. They can enter human body and live there as long as human-host is alive"

"Ha ha ha"

Human beings are funny! They could not put a lock for the virus! They keep their lung open for viruses entry!"

"Ha ha ha"

"Hey! Can I cut your toe nails, Caro?"

 Pin on Feet

 

"Ha ha ha". Why? you want to give me a pedicure?"

"Yeah"

"I could not go for that because of Covid 19. Why do you want to do that service for me?"

"Why not? It is free for you, Caro!"

"I don't think so. Everything has a price, you know"

"What do you mean? I am not going to charge you for that, bitch?"

"I know but I may charge you! Because you might make me wet"

"What!! Why?"

"I think you kind of have foot fetish."

"Really?"

"I am positive. It is not a favor for me. You are doing a favor to yourself. You enjoy touching my toes and foot and making me wet"

"Fuck you, Caro! You want me to cut your nails or not, bitch?"

"Not now. May be tonight."

"Why?"

"I dont know. Not now. Before going to bed would be better"

"OK"

"Thanks"

"Should I remind you?"

"Ha ha ha. I am sure, you will"

"I just get some weird thoughts about fucking human life and the way they live and the way they justify every damn thing as long as the live"

"Oh my God. Again?"

"Have you heard of people saying it is all written down already?. When your time comes you would die or whatever has written down will happen. It could be Corona virus or car accident or cancer or heart attack or whatever. You believe in that?"

"Believe in what? It is all written down already?"

"Yeah"

"I don't know. You are really really spoiling me. You are fucking with my mind and make me nt to believe in anything these days"

"Trust me, you are growing up finally"

 "Fuck you!"

"Any time, white bitch"

"Ha ha ha"

"The funny part is, only after it is over, they would say it is all written down. Until then, they will try edit and rewrite everything."

"So?"

"Life is all about fooling yourself. It is as simple as that"

"Hmm"

"Look at this guy! When he won the swing states he claimed that it is a historic victory. Now he lost not only in MI, PA and WI, but Arizona and  Georgia as well. Now he says it is all election fraud"

"Ha ha ha"

"Guess what?"

"What?"

"He is going to pardon himself before his term ends"

"Seriously?"

"I am serious. He will pardon himself and his lawyer and all his close family members"

"Is that legal?"

"Apparently so. Everybody says President can pardon anybody including himself "

"So, he is untouchable?"

"It seems so"

"Thats terrible"

"I bet your ass, He will not ask Mike Pence to pardon him. He will do it himself"

"Why my ass?"

"Ha hah ha, His ego wont allow someone pardoning him. He would rather do it himself."

"What's the crime?"

"Whatever he has been accused of, I dont know. Including fucking porn stars"

"Did he? He is such a disgusting pig!"

"Idk what he is, honestly. I am glad he will be gone soon"

"All the law suits are failing"

"Hey I watched Virgin river."

"Like it?"

"I watched it. It is watchable but"

"But what?"

"There is nothing new there. I can see what the writer is really up to"

"You dont like it?"

"I just watched it. I could watch it. Hey I am glad I met you, Caro"

"Why now?"

"Idk, I just want to tell you. I dont believe in your western way of saying that I love you every day and calling "honey" either"

"Ha ha ha"

"I would rather love you truly but call you white bitch instead of honey"

" Why?"

"I find it very artificial. Unnatural"

""Honey" just means "hi spouse" or "hi partner" I guess"

"That makes lots of sense, Caro! You are getting better"

"You know what? You think you are superior than white people. Why?"

"Idk about that. But  I dont think I am inferior to anybody"

"Why?"

"Idk, I never have that kind of complex ever"

"I think, you think you are superior than whites"

"Why do you say that?"

"Idk, you have an attitude. You never seem to respect them"

"Are you getting offended because of that?'

"No, I am just wondering why?"

"Then, why I am in love with a white bitch?"

"I dont know. May be you just like fucking white girls"

"Hey, you are only white girl I ever slept with"

"Really?"

"Of course"

"You may sleep with other white women in the future"

"Idk, Are you going to dump me, Caro?"

"I am saying you may dump me"

"I did not dump Sunita. She dumped me!"

"You made her to"

'OK, may be. Trust me, she is happy now"

"I will ask her"

"Go ahead!"

"OK, thanks for letting me!"

 -to be continued

Relax please!